Skrining Tuberkulosis sebagai Strategi Promotif–Preventif dalam Upaya Menekan Risiko Penularan di Masyarakat Lebak
DOI:
https://doi.org/10.69930/scitec.v2i4.613Keywords:
deteksi dini, edukasi kesehatan, kesehatan komunitas, skrining serologis, tuberkulosisAbstract
Tuberkulosis (TB) masih menjadi masalah kesehatan masyarakat global, terutama di wilayah dengan insidensi tinggi seperti Indonesia, di mana keterlambatan diagnosis berkontribusi terhadap berlanjutnya transmisi penyakit. Kegiatan pengabdian berbasis komunitas ini bertujuan untuk mengevaluasi peran skrining serologis sebagai pendekatan promotif–preventif dalam deteksi dini paparan Mycobacterium tuberculosis sekaligus meningkatkan kesadaran masyarakat terhadap pencegahan TB. Sebanyak 59 partisipan dewasa dari komunitas Lebak, Kabupaten Lebak, Banten, mengikuti pemeriksaan antibodi IgM dan IgG anti-TB menggunakan sampel darah vena yang disertai sesi edukasi kesehatan terstruktur. Hasil menunjukkan bahwa seluruh peserta (100%) memiliki hasil IgM non-reaktif, menandakan tidak adanya infeksi aktif, sementara 3 orang (5,1%) menunjukkan IgG reaktif yang mengindikasikan adanya paparan atau infeksi laten sebelumnya. Respon reaktif IgG lebih banyak ditemukan pada perempuan (6,8%) dibanding laki-laki (0%), dan kelompok reaktif memiliki rerata usia lebih muda (32 tahun) dibanding non-reaktif (40 tahun). Temuan ini mengisyaratkan bahwa individu usia produktif dengan mobilitas sosial tinggi memiliki risiko paparan lebih besar. Integrasi skrining antibodi dengan edukasi kesehatan terbukti efektif dalam meningkatkan literasi kesehatan dan deteksi dini risiko TB. Pelaksanaan skrining berbasis komunitas secara rutin, dengan dukungan kader kesehatan lokal, berpotensi menjadi strategi promotif–preventif yang efisien, berkelanjutan, dan berdampak nyata dalam menekan penularan TB di masyarakat.
Downloads
References
Almeida Santos, J., Duarte, R., & Nunes, C. (2021). The impact of age when screening for latent tuberculosis infection - is it a problem? European Journal of Public Health, 31(Supplement_3). https://doi.org/10.1093/eurpub/ckab165.255
Brooks, M. B., Lecca, L., Becerra, M. C., Calderon, R. I., Contreras, C. C., Jimenez, J., Yataco, R. M., Zhang, Z., Murray, M. B., & Huang, C.-C. (2025). The Role of Youths in Within-Household Tuberculosis Transmission: A Household Contact Cohort Study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaf490
Davies, L. R. L., Wang, C., Steigler, P., Bowman, K. A., Fischinger, S., Hatherill, M., Fisher, M., Mbandi, S. K., Rodo, M., Ottenhoff, T. H. M., Dockrell, H. M., Sutherland, J. S., Mayanja-Kizza, H., Boom, W. H., Walzl, G., Kaufmann, S. H. E., Nemes, E., Scriba, T. J., Lauffenburger, D., … Fortune, S. M. (2024). Age and sex influence antibody profiles associated with tuberculosis progression. Nature Microbiology, 9(6), 1513–1525. https://doi.org/10.1038/s41564-024-01678-x
Duffy, D., Nemes, E., Llibre, A., Rouilly, V., Musvosvi, M., Smith, N., Filander, E., Africa, H., Mabwe, S., Jaxa, L., Charbit, B., Mulenga, H., Tameris, M., Walzl, G., Malherbe, S., Thomas, S., Hatherill, M., Bilek, N., Scriba, T. J., … Quintana-Murci, L. (2021). Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacteriu m tuberculosis Infection. Clinical Infectious Diseases, 73(9), e3398–e3408. https://doi.org/10.1093/cid/ciaa1562
Escalante, P., Vadiyala, M. R., Pathakumari, B., Marty, P. K., Van Keulen, V. P., Hilgart, H. R., Meserve, K., Theel, E. S., Peikert, T., Bailey, R. C., & Laniado-Laborin, R. (2023). New diagnostics for the spectrum of asymptomatic TB: from infection to subclinical disease. The International Journal of Tuberculosis and Lung Disease, 27(7), 499–505. https://doi.org/10.5588/ijtld.23.0032
Firmansyah, Y., Hendsun, H., Destra, E., & Aditya, B. (2021). Skrining Faktor Risiko Penularan Penyakit Tuberculosis Paru di RW 001 di Puskesmas Kelurahan Kedaung Kali Angke. Jurnal Medika Hutama, 2(03 April), 960–972. https://jurnalmedikahutama.com/index.php/JMH/article/view/199
Goletti, D., Meintjes, G., Andrade, B. B., Zumla, A., & Shan Lee, S. (2025). Insights from the 2024 WHO Global Tuberculosis Report – More Comprehensive Action, Innovation, and Investments required for achieving WHO End TB goals. International Journal of Infectious Diseases, 150, 107325. https://doi.org/10.1016/j.ijid.2024.107325
Haykal, M. N., Eljatin, D. S., Putri, A. I. W., Karimah, R., Fitriani, F. N., & Fardhani, G. (2024). Improving the Knowledge and Attitudes of Pulmonary Tuberculosis Prevention in the Probolinggo Community with Counseling and the Use of Sobat-TB. Indonesian Journal of Global Health Research, 6(5), 2507–2516. https://doi.org/10.37287/ijghr.v6i5.3480
He, Y., Cao, X., Guo, T., He, Y., Du, Y., Zhang, H., Feng, B., Du, J., Zhang, B., Wang, K., Yan, J., Wang, D., Liu, Z., Pan, S., Xin, H., & Gao, L. (2022). Serial testing of latent tuberculosis infection in patients with diabetes mellitus using interferon-gamma release assay, tuberculin skin test, and creation tuberculin skin test. Frontiers in Public Health, 10. https://doi.org/10.3389/fpubh.2022.1025550
Kim, H., Beach, S., Friedman, E., Donovan, H., & Schulz, R. (2023). EFFECTS OF CHILDCARE, WORK, AND CAREGIVING INTENSITY ON MALE AND FEMALE FAMILY CAREGIVERS. Innovation in Aging, 7(Supplement_1), 819–820. https://doi.org/10.1093/geroni/igad104.2644
Li, A., Yuan, S., Li, Q., Li, J., Yin, X., & Liu, N. (2023). Prevalence and risk factors of malnutrition in patients with pulmonary tuberculosis: a systematic review and meta-analysis. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1173619
Lv, H., Wang, L., Zhang, X., Dang, C., Liu, F., Zhang, X., Bai, J., You, S., Chen, H., Zhang, W., & Xu, Y. (2024). Further analysis of tuberculosis in eight high-burden countries based on the Global Burden of Disease Study 2021 data. Infectious Diseases of Poverty, 13(1), 70. https://doi.org/10.1186/s40249-024-01247-8
Martineau, A. R., Chandran, S., Palukani, W., Garrido, P., Mayito, J., Reece, S. T., & Tiwari, D. (2024). Toward a molecular microbial blood test for tuberculosis infection. International Journal of Infectious Diseases, 141, 106988. https://doi.org/10.1016/j.ijid.2024.106988
Martinez, L., Seddon, J. A., Horsburgh, C. R., Lange, C., Mandalakas, A. M., Martinez, L., Seddon, J., Liu, Q., Acuna Villaorduna, C., Bonnet, M., Carvalho, A. C. C., Chan, P.-C., Hill, P. C., Lopez-Varela, E., Donkor, S., Graham, S. M., Villalba, J. A., Grandjean, L., Zellweger, J.-P., … Mandalakas, A. M. (2024). Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies. The Lancet Respiratory Medicine, 12(8), 633–641. https://doi.org/10.1016/S2213-2600(24)00083-3
Melkie, S. T., Arias, L., Farroni, C., Jankovic Makek, M., Goletti, D., & Vilaplana, C. (2022). The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy: a review from the ESGMYC study group. European Respiratory Review, 31(163), 210218. https://doi.org/10.1183/16000617.0218-2021
Mitchell, E., Graham, A. L., Úbeda, F., & Wild, G. (2022). On maternity and the stronger immune response in women. Nature Communications, 13(1), 4858. https://doi.org/10.1038/s41467-022-32569-6
Pickering, C., & Wood, L. (2024). IMPACT OF GENDER FOR ELDER MISTREATMENT WITHIN DEMENTIA FAMILY CAREGIVING. Innovation in Aging, 8(Supplement_1), 154–154. https://doi.org/10.1093/geroni/igae098.0496
Sinha, P., Davis, J., Saag, L., Wanke, C., Salgame, P., Mesick, J., Horsburgh, C. R., & Hochberg, N. S. (2019). Undernutrition and Tuberculosis: Public Health Implications. The Journal of Infectious Diseases, 219(9), 1356–1363. https://doi.org/10.1093/infdis/jiy675
Stepniak, C., Suitor, J. J., & Gilligan, M. (2024). BALANCING HEALTH AND CAREGIVING: ADULT CHILDREN’S HEALTH PROBLEMS IMPACT ON CAREGIVING. Innovation in Aging, 8(Supplement_1), 397–398. https://doi.org/10.1093/geroni/igae098.1293
Vasiliu, A., Martinez, L., Gupta, R. K., Hamada, Y., Ness, T., Kay, A., Bonnet, M., Sester, M., Kaufmann, S. H. E., Lange, C., & Mandalakas, A. M. (2024). Tuberculosis prevention: current strategies and future directions. Clinical Microbiology and Infection, 30(9), 1123–1130. https://doi.org/10.1016/j.cmi.2023.10.023
Wang, L., Xu, C., Hu, M., Qiao, J., Chen, W., Li, T., Qian, S., & Yan, M. (2021). Spatio-temporal variation in tuberculosis incidence and risk factors for the disease in a region of unbalanced socio-economic development. BMC Public Health, 21(1), 1817. https://doi.org/10.1186/s12889-021-11833
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Donatila Mano S., Alexander Halim Santoso, Bryan Anna Wijaya, Cristian Alexandro, Haritsyah Hekmatyar

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.















